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Аclinical case of newly diagnosed opticoneuromyelitis (Devik's disease)

https://dx.doi.org/10.51350/zdravkg2024.2.6.10.78.84
Аclinical case of newly diagnosed opticoneuromyelitis (Devik's disease)
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Abstract About the authors References

Abstract

Introduction. Opticoneuromyelitis, or Devik's syndrome, is an inflammatory demyelinating disease of the central nervous system, affecting mainly the optic nerve and spinal cord. The clinical picture is characterized by a combination of syndromes of optic neuritis and longitudinally transverse myelitis. Imaging techniques such as optical coherence tomography, evoked potentials, and magnetic resonance imaging are used for diagnosis. Currently, the key method of making a correct diagnosis is the detection of a specific serological marker — antibodies to aquaporin-4 (NMO-IgG), the titer of which correlates with the activity of the disease and helps to conduct differential diagnosis. The purpose of the study. To analyze the current scientific literature on Devik's opticoneuromyelitis and present a clinical case report from our clinical practice. Materials and methods. In the patient whose medical history was described in this article, the diagnosis was established based on diagnostic criteria for ONM Devika. Results. In a 41-year-old young woman, neurological symptoms were represented by optic neuritis, myelitis and pelvic organ dysfunction. The diagnosis was confirmed based on the medical history of the disease, as well as neuroimaging and laboratory studies. Conclusion. With timely diagnosis and adequate pathogenetic therapy, Devika's opticoneuromyelitis has a relatively good prognosis and the potential to restore lost motor and visual functions.

About the authors

Акматова Мира Сулаймановна, Врач невролог Клинической больницы скорой медицинской помощи г. Бишкека,отделение неотложной неврологии, Бишкек, Кыргызская Республика
Жолдошев Эмир Кылычбекович, завуч кафедры кафедры Неврологии и клинической генетики Кыргызской государственной медицинской академии им. И.К. Ахунбаева, Бишкек, Кыргызская Республика
Абдиманапова Гулбурак Абдиманаповна, ассистент кафедры пропедевтики внутреннех болезней с курсом энжокринологии и профпатологии Кыргызской государственной медицинской академии им. И.К. Ахунбаева, Бишкек, Кыргызская Республика

Akmatova Mira Sulaymanovna, Neurologist, Bishkek Clinical Emergency Hospital, Department of Emergency Neurology, Bishkek, Kyrgyz Republic
Zholdoshev Emir Kylychbekovich, Head of the Department of Neurology and Clinical Genetics of the Kyrgyz State Medical Academy named after I.K. Akhunbaeva, Bishkek, Kyrgyz Republic

Abdimanapova Gulburak Abdimanapovna, assistant of the Department of Propaedeutics of Internal Diseases with a course in endocrinology and occupational pathology of the Kyrgyz State Medical Academy
named after I.K. Akhunbaeva, Bishkek, Kyrgyz Republic

Акматова Мира Сулаймановна, Бишкек шаардык клиникалык тез жардам ооруканасынын тез жардам неврология бөлүмүнүн невропатологу, Бишкек, Кыргыз Республикасы

Жолдошев Эмир Кылычбекович, И.К. Ахунбаев атындагы Кыргыз мамлекеттик медициналык академиясынын неврология жана клиникалык генетика кафедрасынын башчысы, Бишкек, Кыргыз Республикасы

Абдиманапова Гулбурак Абдиманаповна, И.К. Ахунбаев атындагы Кыргыз мамлекеттик медициналык академиясынын ингринология жана профессионалдык патология курсу менен ички оорулардын пропедевтикасы кафедрасынын ассистенти, Бишкек, Кыргыз Республикасы

 

References

1. Wingerchuk DM, Lennon VA, Pittock SJ, et al. Neurology Revised diagnostic criteria for neuromyelitis optica 2006;
66:1485–1489. [PubMed] [Google Scholar]
2. Wingerchuk DM, Lennon VA, Lucchinetti CF, et al.The spectrum of neuromyelitis optica. Lancet Neurol 2007; 6:805–
815.
3. Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water
channel. J Exp Med 2005; 202:473–477. [PMC free article][PubMed] [Google Scholar]
4. Wingerchuk DM, Hogancamp WF, O’Brien PC, et al. The clinical course of neuromyelitis optica (Devic's syndrome).
Neurology 1999;53:1107–1114. [PubMed] [Google Scholar]
5. Wingerchuk DM, Banwell B, Bennett JL, et al. International consensus diagnostic criteria for neuromyelitis optica spec
trum disorders. Neurology 2015;85:177–189. [PMC free article] [PubMed] [Google Scholar]
6. Krishnan C, Kaplin AI, Pardo CA, et al.. Demyelinating disorders: update on transverse myelitis. Curr Neurol Neurosci
Rep 2006;6:236–43. 10.1007/s11910-006-0011-1.
7. Yaregal S, Bekele N, Gebrewold Y, Tadesse A. Neuromyelitis Optica Spectrum Disorder: A Case Report. Int Med Ca
se Rep J. 2021 Sep 21;14:643-648. doi: 10.2147/IMCRJ. S334362. PMID: 34584464; PMCID: PMC8464318.
8. Papp V, Magyari M, Aktas O, Berger T, Broadley SA, Cabre P, Jacob A, Kira JI, Leite MI, Marignier R, Miyamoto K,
Palace J, Saiz A, Sepulveda M, Sveinsson O, Illes Z. World wide Incidence and Prevalence of Neuromyelitis Optica: A
Systematic Review. Neurology. 2021 Jan 12;96(2):59-77. doi: 10.1212/WNL.0000000000011153. Epub 2020 Dec 11.
PMID: 33310876; PMCID: PMC7905781.
9. Яхно Н.И., Мозолевский Ю.В., Голубева В.В. и др. Оптикомиелит Девика // Неврологический журнал.2008.Т.
13, № 2. С. 27–32.
10. Held F, Klein AK, Berthele A. Drug Treatment of Neu romyelitis Optica Spectrum Disorders: Out with the Old, in with
the New? Immunotargets Ther. 2021 Mar 19;10:87-101.doi:10.2147/ITT.S287652. PMID:33777853; PMCID: PM
C79 89551.

1. Wingerchuk DM, Lennon VA, Pittock SJ, et al. Neurology Revised diagnostic criteria for neuromyelitis optica 2006;
66:1485–1489. [PubMed] [Google Scholar]
2. Wingerchuk DM, Lennon VA, Lucchinetti CF, et al.The spectrum of neuromyelitis optica. Lancet Neurol 2007; 6:805–
815.
3. Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water
channel. J Exp Med 2005; 202:473–477. [PMC free article][PubMed] [Google Scholar]
4. Wingerchuk DM, Hogancamp WF, O’Brien PC, et al. The clinical course of neuromyelitis optica (Devic's syndrome).
Neurology 1999;53:1107–1114. [PubMed] [Google Scholar]
5. Wingerchuk DM, Banwell B, Bennett JL, et al. International consensus diagnostic criteria for neuromyelitis optica spec
trum disorders. Neurology 2015;85:177–189. [PMC free article] [PubMed] [Google Scholar]
6. Krishnan C, Kaplin AI, Pardo CA, et al.. Demyelinating disorders: update on transverse myelitis. Curr Neurol Neurosci
Rep 2006;6:236–43. 10.1007/s11910-006-0011-1.
7. Yaregal S, Bekele N, Gebrewold Y, Tadesse A. Neuromyelitis Optica Spectrum Disorder: A Case Report. Int Med Ca
se Rep J. 2021 Sep 21;14:643-648. doi: 10.2147/IMCRJ. S334362. PMID: 34584464; PMCID: PMC8464318.
8. Papp V, Magyari M, Aktas O, Berger T, Broadley SA, Cabre P, Jacob A, Kira JI, Leite MI, Marignier R, Miyamoto K,
Palace J, Saiz A, Sepulveda M, Sveinsson O, Illes Z. World wide Incidence and Prevalence of Neuromyelitis Optica: A
Systematic Review. Neurology. 2021 Jan 12;96(2):59-77. doi: 10.1212/WNL.0000000000011153. Epub 2020 Dec 11.
PMID: 33310876; PMCID: PMC7905781.
9. Яхно Н.И., Мозолевский Ю.В., Голубева В.В. и др. Оптикомиелит Девика // Неврологический журнал.2008.Т.
13, № 2. С. 27–32.
10. Held F, Klein AK, Berthele A. Drug Treatment of Neu romyelitis Optica Spectrum Disorders: Out with the Old, in with
the New? Immunotargets Ther. 2021 Mar 19;10:87-101.doi:10.2147/ITT.S287652. PMID:33777853; PMCID: PM
C79 89551.

1. Wingerchuk DM, Lennon VA, Pittock SJ, et al. Neurology Revised diagnostic criteria for neuromyelitis optica 2006;
66:1485–1489. [PubMed] [Google Scholar]
2. Wingerchuk DM, Lennon VA, Lucchinetti CF, et al.The spectrum of neuromyelitis optica. Lancet Neurol 2007; 6:805–
815.
3. Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water
channel. J Exp Med 2005; 202:473–477. [PMC free article][PubMed] [Google Scholar]
4. Wingerchuk DM, Hogancamp WF, O’Brien PC, et al. The clinical course of neuromyelitis optica (Devic's syndrome).
Neurology 1999;53:1107–1114. [PubMed] [Google Scholar]
5. Wingerchuk DM, Banwell B, Bennett JL, et al. International consensus diagnostic criteria for neuromyelitis optica spec
trum disorders. Neurology 2015;85:177–189. [PMC free article] [PubMed] [Google Scholar]
6. Krishnan C, Kaplin AI, Pardo CA, et al.. Demyelinating disorders: update on transverse myelitis. Curr Neurol Neurosci
Rep 2006;6:236–43. 10.1007/s11910-006-0011-1.
7. Yaregal S, Bekele N, Gebrewold Y, Tadesse A. Neuromyelitis Optica Spectrum Disorder: A Case Report. Int Med Ca
se Rep J. 2021 Sep 21;14:643-648. doi: 10.2147/IMCRJ. S334362. PMID: 34584464; PMCID: PMC8464318.
8. Papp V, Magyari M, Aktas O, Berger T, Broadley SA, Cabre P, Jacob A, Kira JI, Leite MI, Marignier R, Miyamoto K,
Palace J, Saiz A, Sepulveda M, Sveinsson O, Illes Z. World wide Incidence and Prevalence of Neuromyelitis Optica: A
Systematic Review. Neurology. 2021 Jan 12;96(2):59-77. doi: 10.1212/WNL.0000000000011153. Epub 2020 Dec 11.
PMID: 33310876; PMCID: PMC7905781.
9. Яхно Н.И., Мозолевский Ю.В., Голубева В.В. и др. Оптикомиелит Девика // Неврологический журнал.2008.Т.
13, № 2. С. 27–32.
10. Held F, Klein AK, Berthele A. Drug Treatment of Neu romyelitis Optica Spectrum Disorders: Out with the Old, in with
the New? Immunotargets Ther. 2021 Mar 19;10:87-101.doi:10.2147/ITT.S287652. PMID:33777853; PMCID: PM
C79 89551.

Keywords
Opticoneuromyelitis , Devik syndrome , Autoimmune pathology , Antibodies to aquaporin-4
Для цитирования

Акматова М.С., Жолдошев Э.К., Абдиманапова Г.А. Клинический случай впервые выявленного оптиконейромиелита (болезнь Девика). Научно-практический журнал «Здравоохранение Кыргызстана» 2024, № 2, с.78-84. https://dx.doi.org/10.51350/zdravkg2024.2.6.10.78.84
For citation

Akmatova M.S., Zholdoshev E.K., Abdimanapova G.A.Аclinical case of newly diagnosed opticoneu romyelitis (Devik's
disease). Scientific and practical journal “Health care of Kyrgyzstan” 2024, No.2, p. 78-84.  https://dx.doi.org/10.51350/zdravkg2024.2.6.10.78.84
Цитата үчүн

Акматова М.С., Жолдошев Э.К., Абдиманапова Г.А. Жаңы аныкталган клиникалык учур оптиконевромиелит (Девик оорусу). "Кыргызстандын саламаттык сактоо"  илимий-практикалык журналы 2024, № 2, б. 78-84. https://dx.doi.org/10.51350/zdravkg2024.2.6.10.78.84
Authors Akmatova M.S., Shleifer S.G., Zholdoshev E.K., Abdimanapova G.A.
Link doi.org https://dx.doi.org/10.51350/zdravkg2024.2.6.10.78.84
Pages 78-84
Keywords Opticoneuromyelitis , Devik syndrome, Autoimmune pathology, Antibodies to aquaporin-4
Russian
Об авторах

Акматова Мира Сулаймановна, Врач невролог Клинической больницы скорой медицинской помощи г. Бишкека,отделение неотложной неврологии, Бишкек, Кыргызская Республика
Жолдошев Эмир Кылычбекович, завуч кафедры кафедры Неврологии и клинической генетики Кыргызской государственной медицинской академии им. И.К. Ахунбаева, Бишкек, Кыргызская Республика
Абдиманапова Гулбурак Абдиманаповна, ассистент кафедры пропедевтики внутреннех болезней с курсом энжокринологии и профпатологии Кыргызской государственной медицинской академии им. И.К. Ахунбаева, Бишкек, Кыргызская Республика

Полный текст

PDF (RUS)
Список литературы

1. Wingerchuk DM, Lennon VA, Pittock SJ, et al. Neurology Revised diagnostic criteria for neuromyelitis optica 2006;
66:1485–1489. [PubMed] [Google Scholar]
2. Wingerchuk DM, Lennon VA, Lucchinetti CF, et al.The spectrum of neuromyelitis optica. Lancet Neurol 2007; 6:805–
815.
3. Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water
channel. J Exp Med 2005; 202:473–477. [PMC free article][PubMed] [Google Scholar]
4. Wingerchuk DM, Hogancamp WF, O’Brien PC, et al. The clinical course of neuromyelitis optica (Devic's syndrome).
Neurology 1999;53:1107–1114. [PubMed] [Google Scholar]
5. Wingerchuk DM, Banwell B, Bennett JL, et al. International consensus diagnostic criteria for neuromyelitis optica spec
trum disorders. Neurology 2015;85:177–189. [PMC free article] [PubMed] [Google Scholar]
6. Krishnan C, Kaplin AI, Pardo CA, et al.. Demyelinating disorders: update on transverse myelitis. Curr Neurol Neurosci
Rep 2006;6:236–43. 10.1007/s11910-006-0011-1.
7. Yaregal S, Bekele N, Gebrewold Y, Tadesse A. Neuromyelitis Optica Spectrum Disorder: A Case Report. Int Med Ca
se Rep J. 2021 Sep 21;14:643-648. doi: 10.2147/IMCRJ. S334362. PMID: 34584464; PMCID: PMC8464318.
8. Papp V, Magyari M, Aktas O, Berger T, Broadley SA, Cabre P, Jacob A, Kira JI, Leite MI, Marignier R, Miyamoto K,
Palace J, Saiz A, Sepulveda M, Sveinsson O, Illes Z. World wide Incidence and Prevalence of Neuromyelitis Optica: A
Systematic Review. Neurology. 2021 Jan 12;96(2):59-77. doi: 10.1212/WNL.0000000000011153. Epub 2020 Dec 11.
PMID: 33310876; PMCID: PMC7905781.
9. Яхно Н.И., Мозолевский Ю.В., Голубева В.В. и др. Оптикомиелит Девика // Неврологический журнал.2008.Т.
13, № 2. С. 27–32.
10. Held F, Klein AK, Berthele A. Drug Treatment of Neu romyelitis Optica Spectrum Disorders: Out with the Old, in with
the New? Immunotargets Ther. 2021 Mar 19;10:87-101.doi:10.2147/ITT.S287652. PMID:33777853; PMCID: PM
C79 89551.

Для цитирования

Акматова М.С., Жолдошев Э.К., Абдиманапова Г.А. Клинический случай впервые выявленного оптиконейромиелита (болезнь Девика). Научно-практический журнал «Здравоохранение Кыргызстана» 2024, № 2, с.78-84. https://dx.doi.org/10.51350/zdravkg2024.2.6.10.78.84
English
About authors

Akmatova Mira Sulaymanovna, Neurologist, Bishkek Clinical Emergency Hospital, Department of Emergency Neurology, Bishkek, Kyrgyz Republic
Zholdoshev Emir Kylychbekovich, Head of the Department of Neurology and Clinical Genetics of the Kyrgyz State Medical Academy named after I.K. Akhunbaeva, Bishkek, Kyrgyz Republic

Abdimanapova Gulburak Abdimanapovna, assistant of the Department of Propaedeutics of Internal Diseases with a course in endocrinology and occupational pathology of the Kyrgyz State Medical Academy
named after I.K. Akhunbaeva, Bishkek, Kyrgyz Republic
References

1. Wingerchuk DM, Lennon VA, Pittock SJ, et al. Neurology Revised diagnostic criteria for neuromyelitis optica 2006;
66:1485–1489. [PubMed] [Google Scholar]
2. Wingerchuk DM, Lennon VA, Lucchinetti CF, et al.The spectrum of neuromyelitis optica. Lancet Neurol 2007; 6:805–
815.
3. Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water
channel. J Exp Med 2005; 202:473–477. [PMC free article][PubMed] [Google Scholar]
4. Wingerchuk DM, Hogancamp WF, O’Brien PC, et al. The clinical course of neuromyelitis optica (Devic's syndrome).
Neurology 1999;53:1107–1114. [PubMed] [Google Scholar]
5. Wingerchuk DM, Banwell B, Bennett JL, et al. International consensus diagnostic criteria for neuromyelitis optica spec
trum disorders. Neurology 2015;85:177–189. [PMC free article] [PubMed] [Google Scholar]
6. Krishnan C, Kaplin AI, Pardo CA, et al.. Demyelinating disorders: update on transverse myelitis. Curr Neurol Neurosci
Rep 2006;6:236–43. 10.1007/s11910-006-0011-1.
7. Yaregal S, Bekele N, Gebrewold Y, Tadesse A. Neuromyelitis Optica Spectrum Disorder: A Case Report. Int Med Ca
se Rep J. 2021 Sep 21;14:643-648. doi: 10.2147/IMCRJ. S334362. PMID: 34584464; PMCID: PMC8464318.
8. Papp V, Magyari M, Aktas O, Berger T, Broadley SA, Cabre P, Jacob A, Kira JI, Leite MI, Marignier R, Miyamoto K,
Palace J, Saiz A, Sepulveda M, Sveinsson O, Illes Z. World wide Incidence and Prevalence of Neuromyelitis Optica: A
Systematic Review. Neurology. 2021 Jan 12;96(2):59-77. doi: 10.1212/WNL.0000000000011153. Epub 2020 Dec 11.
PMID: 33310876; PMCID: PMC7905781.
9. Яхно Н.И., Мозолевский Ю.В., Голубева В.В. и др. Оптикомиелит Девика // Неврологический журнал.2008.Т.
13, № 2. С. 27–32.
10. Held F, Klein AK, Berthele A. Drug Treatment of Neu romyelitis Optica Spectrum Disorders: Out with the Old, in with
the New? Immunotargets Ther. 2021 Mar 19;10:87-101.doi:10.2147/ITT.S287652. PMID:33777853; PMCID: PM
C79 89551.

For citation

Akmatova M.S., Zholdoshev E.K., Abdimanapova G.A.Аclinical case of newly diagnosed opticoneu romyelitis (Devik's
disease). Scientific and practical journal “Health care of Kyrgyzstan” 2024, No.2, p. 78-84.  https://dx.doi.org/10.51350/zdravkg2024.2.6.10.78.84
Kyrgyz
Авторлор жөнүндө

Акматова Мира Сулаймановна, Бишкек шаардык клиникалык тез жардам ооруканасынын тез жардам неврология бөлүмүнүн невропатологу, Бишкек, Кыргыз Республикасы

Жолдошев Эмир Кылычбекович, И.К. Ахунбаев атындагы Кыргыз мамлекеттик медициналык академиясынын неврология жана клиникалык генетика кафедрасынын башчысы, Бишкек, Кыргыз Республикасы

Абдиманапова Гулбурак Абдиманаповна, И.К. Ахунбаев атындагы Кыргыз мамлекеттик медициналык академиясынын ингринология жана профессионалдык патология курсу менен ички оорулардын пропедевтикасы кафедрасынын ассистенти, Бишкек, Кыргыз Республикасы

 
Шилтемелер

1. Wingerchuk DM, Lennon VA, Pittock SJ, et al. Neurology Revised diagnostic criteria for neuromyelitis optica 2006;
66:1485–1489. [PubMed] [Google Scholar]
2. Wingerchuk DM, Lennon VA, Lucchinetti CF, et al.The spectrum of neuromyelitis optica. Lancet Neurol 2007; 6:805–
815.
3. Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water
channel. J Exp Med 2005; 202:473–477. [PMC free article][PubMed] [Google Scholar]
4. Wingerchuk DM, Hogancamp WF, O’Brien PC, et al. The clinical course of neuromyelitis optica (Devic's syndrome).
Neurology 1999;53:1107–1114. [PubMed] [Google Scholar]
5. Wingerchuk DM, Banwell B, Bennett JL, et al. International consensus diagnostic criteria for neuromyelitis optica spec
trum disorders. Neurology 2015;85:177–189. [PMC free article] [PubMed] [Google Scholar]
6. Krishnan C, Kaplin AI, Pardo CA, et al.. Demyelinating disorders: update on transverse myelitis. Curr Neurol Neurosci
Rep 2006;6:236–43. 10.1007/s11910-006-0011-1.
7. Yaregal S, Bekele N, Gebrewold Y, Tadesse A. Neuromyelitis Optica Spectrum Disorder: A Case Report. Int Med Ca
se Rep J. 2021 Sep 21;14:643-648. doi: 10.2147/IMCRJ. S334362. PMID: 34584464; PMCID: PMC8464318.
8. Papp V, Magyari M, Aktas O, Berger T, Broadley SA, Cabre P, Jacob A, Kira JI, Leite MI, Marignier R, Miyamoto K,
Palace J, Saiz A, Sepulveda M, Sveinsson O, Illes Z. World wide Incidence and Prevalence of Neuromyelitis Optica: A
Systematic Review. Neurology. 2021 Jan 12;96(2):59-77. doi: 10.1212/WNL.0000000000011153. Epub 2020 Dec 11.
PMID: 33310876; PMCID: PMC7905781.
9. Яхно Н.И., Мозолевский Ю.В., Голубева В.В. и др. Оптикомиелит Девика // Неврологический журнал.2008.Т.
13, № 2. С. 27–32.
10. Held F, Klein AK, Berthele A. Drug Treatment of Neu romyelitis Optica Spectrum Disorders: Out with the Old, in with
the New? Immunotargets Ther. 2021 Mar 19;10:87-101.doi:10.2147/ITT.S287652. PMID:33777853; PMCID: PM
C79 89551.

Цитата үчүн

Акматова М.С., Жолдошев Э.К., Абдиманапова Г.А. Жаңы аныкталган клиникалык учур оптиконевромиелит (Девик оорусу). "Кыргызстандын саламаттык сактоо"  илимий-практикалык журналы 2024, № 2, б. 78-84. https://dx.doi.org/10.51350/zdravkg2024.2.6.10.78.84
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