Abstract
Abstract
Introduction. The problem of radiation exposure to the morphology of the testes is relevant. Aim. Study of morphological changes in rat testicles after general external gamma irradiation. Material and methods. We prepared histological sections of rat testicles subjected to general single gamma irradiation at doses of 0, 5 and 1,0 Gy, stained with hematoxylin-eosin paint. The number of transversely cut convoluted seminal tubules in the field of view was calculated. According to the state of the spermatogenic epithelium, the convoluted seminal tubules were divided into five types. Results. It was found that after 90 days from the moment of irradiation, the number of convoluted tubules of type I decreased, respectively, in preparations of subgroups 0,5 and 1,0 Gy to (-50,3% and -66,9%) p<0.05 relative to the control. The number of convoluted tubules of type II and III increased by 75% and 140% p<0,05, 363% and 652% p<0,05, respectively, for doses of 0,5 and 1,0 Gy compared with the control. Also in 2 experimental groups there were tubules of type V, the number of which was more than 2%. Conclusions. By three months after the total single gamma radiation at doses of 0, 5 and 1, 0 Gy, pathomorphological changes in the structures of the testes occur, more pronounced in the destruction of the spermatogenic epithelium of the tubules. This will inevitably lead to cell deformation, disruption of their functions and, consequently, disruption of the function of the male reproductive system.