№2 (2023)

Introduction. The high informative effective activity of innovative technologies introduced into the practical work of the diagnostic service of a multidisciplinary hospital in the form of a preventive medicine department functioning in the Check-up format, a laboratory of personalized genomic diagnostics, centers of nuclear medicine, CT and MRI studies is shown. The data obtained from the analysis of the use of innovative high-precision diagnostic technologies are presented and an assessment of their informative effectiveness in identifying early forms of diseases and pre-pathological signs of hereditary and oncological diseases that contribute to the timely taking of therapeutic and recreational measures is given.
Objective. To analyze the state and evaluate the effectiveness of the introduction and use of innovative diagnostic technologies in the practice of a multidisciplinary hospital.
Methods. The activities of the Department of Preventive Medicine in the Check-up format, quantitative and structural indicators of the laboratory of genomic diagnostics, nuclear medicine centers, computed tomography (CT) and magnetic tomography (MRI) studies with an assessment of the informativeness of each method in the diagnosis of early or pre-pathological forms of various hereditary and oncological diseases.
Results. The use of innovative technology in the form of a Check-up made it possible in a very short time (only 1-2 days) to conduct a full screening examination of persons from among the attached population, identify early forms of the disease or signs of various diseases and timely organize therapeutic measures in the presence of identified pathological processes or measures to level their risk factors and improve patients' health. The use of innovative non- and minimally invasive diagnostic methods made it possible to make an accurate early diagnosis (or pre-pathological diagnosis of diseases) and determine further adequate tactics of treatment and rehabilitation of patients according to approved clinical protocols.
Conclusion. Innovative technologies introduced into the practice of the diagnostic service of the multidisciplinary hospital have shown high informative effectiveness based on the widened range of high-precision methods, including the services of the department of preventive medicine in the Check-up format, the laboratory of personalized genomic diagnostics, nuclear medicine centers, CT and MRI studies.

The study shows the effect of the biologically active additive «Selecor» on lipid metabolism in the blood of
persons of extreme professions. It was revealed that the use of «Selecor» tablets containing selenium at a dose of 20 mcg,
two tablets for 21-30 days causes a significant decrease in the level of cholesterol and its precursors in the blood, which
indicates the antiatherogenic effect of «Selecor» and allows us to recommend it as an additional means of prevention and
treatment of patients with atherosclerosis.

Introduction. Congenital intestinal obstruction in newborns remains a major cause requiring careful diagnosis
and emergency surgical intervention in the neonatal period.
Objective of the study. To analyze the growth of congenital intestinal obstruction, surgical tactics and results of its treatment in newborn congenital intestinal obstruction.
Materials and Methods. 165 newborns with congenital intestinal obstruction were investigated in National Center for
Maternal and Child Health Protection. Of them 88 (53,3%) were boys and 77 (46,7%) were girls diagnosed with congenital intestinal obstruction.
Results and Discussion. Out of 165 (16.2%) neonates admitted with congenital intussusception, 20 (1.96%) children
were diagnosed with high intussusception. Low bowel obstruction was diagnosed in 145 (14.2%) children. Most frequently, multiple congenital malformations were detected in newborns with high bowel obstruction, so combined congenital heart defects and Down syndrome were noted in 12 (%) patients. In low intestinal obstruction, newborns rarely
had multiple congenital malformations.
Conclusions. The performed analysis indicates that it is necessary to develop neonatal surgical service in the Kyrgyz Republic to provide timely and qualified assistance to newborns with congenital intestinal obstruction.
The article analyzes the growth of congenital abnormalities of the gastrointestinal tract causing high intestinal obstruction
in newborns in the regions of the Kyrgyz Republic. The malformations most frequently causing high intestinal obstruction
and methods of their correction in children are determined.

Introduction. This research paper describes a clinical case of an infiltrative and nasal form of zooanthroponous
trichophytosis in a 9-year-old boy. Trichophytosis is a skin disease that can affect the scalp, body and nails. The infiltrative-inflammatory form is one of the most severe clinical variants of trichophytosis, which is characterized by inflammatory skin changes and suppuration.
The aim of the study. This paper describes the case of a 9-year-old child who presented with symptoms of infiltrative and
fungal trichophytosis of the scalp.
Materials and methods. The diagnosis of the disease was based on clinical findings and the result of mycological investigations. A culture study showed he presence of Trichophyton verrucosum fungus in skin samples. Treatment was carried
out with antimycotic drugs for 8 weeks. In addition, measures were taken to prevent the spread of the disease, including
personal hygiene, disinfection of articles of use and thorough treatment of clothing and bedding.
Results. The importance of timely diagnosis of this mycotic infection in order to prevent the development of widespread
suppuration processes, leading to a permanent cosmetic defect in the form of foci of cicatricial atrophy of the scalp, was
indicated.
Conclusions. There was a good effect of treatment with fluconazole and local therapy with lotions with potassium permanganate, hypertonic sodium chloride solution and 20% ichthyol ointment.

Introduction. The article describes a rare clinical case of acute varioliform Mucha — Habermann parapsoriasis in a six-year-old child. This rare dermatosis is characterized by the presence of spots and/or papules covered with smallplate scales. Clinical observation of this case is of interest to practicing dermatologists due to the rare occurrence of this disease in children, the complexity of differential diagnostic search.
The aim of the study. Description of a clinical case of acute varioliform parapsoriasis of Gaberman-Much in a 6-year-old
boy. Materials and methods. Review of domestic and foreign literature sources describing the current features of the course of parapsoriasis, using the search engines PubMed, Medline, SCOPUS, RSCI. Description of the clinical case. Results. A good effect was obtained from detoxification therapy with isotonic sodium chloride solution (0.9%) and local therapy with glucocorticosteroid and antibacterial ointments, aniline dyes. Conclusions.The case is presented to draw the attention of the medical community to the problem of acute parapsoriasis.

Introduction. Diaphragmatic hernia is a combined malformation that affects both the organs of the respiratory
system, the cardiovascular system, and the organs of the digestive system.
The aim of the study- To study the case histories of children with diaphragm pathology who were treated in Children's
Clinical Emergency Hospital of Bishkek city
Materials and methods. An analysis was made of 73 cases of children with diaphragm defects, of which 69 (94.5%) received surgical treatment in the departments of emergency neonatology and thoracic surgery for the period 2012-2022.
Results. According to the localization of the defect in the diaphragm - hernia of the dome itself - 58 (79.5%), of which
12 (20.7%) had relaxation of the right dome. 46 (79.3%) children had hernias of the left dome, of which 36 (78.3%) were
false, 10 (21.7%) were true. Hiatus hernias - 13 (17.8%), and in 2 (2.7%) people - anterior hernias. In 8 (10.9%) people,
hernias appeared as a result of previous heart surgeries (congenital malformations of VSD-6, PDA-1, Tetralogy of Fallot-1), of which only 4 (50%) were operated on due to the development respiratory failure, and the rest were diagnosed
with relaxation
Conclusions. 1. The most common diaphragmatic hernias are hernias of the dome itself - 79.5% of the total number of
those examined. 2. In 5.5% of cases, children are not shown surgical treatment, because. Were a complication of previous
heart surgery. 3. 17.8% of children were identified in whom diaphragmatic hernias proceeded under the guise of other
somatic and neurological diseases, and therefore a routine x-ray of the chest cavity organs in 2 projections was recommended for vomiting syndrome, routine blood tests. 4. Mortality in children under 2 months was 11.6% of the total
number of operations.

The COVID-19 pandemic has seriously undermined the progress made in the fight against tuberculosis worldwide over the past 10 years. In 2020, compared to 2019, due to restrictions on access to tuberculosis treatment services,
reduced funding for TB services and programs, there was a decrease in the registration of TB cases, a reduction in the
detection of TB of all ages, children and MDR TB by up to 40%, as well as a reduction in preventive TB treatment of household contacts and people living with HIV. In addition, the staff of the tuberculosis service was redistributed to other
functions.
According to the World Health Organization: 8 million new cases of tuberculosis are registered annually in the world, 2
million patients die. If this trend continues, many experts express fears that the COVID-19 pandemic may lead to a deterioration in the epidemiological situation of tuberculosis.
Studies conducted in 2020 showed that if the COVID-19 pandemic on a global scale leads to a 25% decrease in the expected levels of TB detection within 6 months, then we can expect an increase in tuberculosis mortality by 26%, which
will return us to the levels of tuberculosis mortality observed in 2012 [1]. In 2020, treatment for tuberculosis decreased
by 21% compared to 2019 [2].
According to the early modeling conducted in 2020, it is expected that in the period from 2020 to 2025 another 1.4 million
people will die from tuberculosis as a direct consequence of the COVID-19 pandemic, which is significantly more than
from any other infection [3]. All this will worsen the situation with tuberculosis in the world, achieved five years ago,
and will cast doubt on the implementation of the goal put forward by world leaders – to end tuberculosis by 2030.
Objective: to review the situation of tuberculosis incidence during the pandemic.
Materials and methods of research. The materials for studying the effect of COVID-19 on tuberculosis were statistical
data on the registration of diseases.
Results and discussion. In 2020, in the Kyrgyz Republic, as well as throughout the world, the detection rate of tuberculosis
decreased seriously. According to experts, the number of new cases has decreased not because the disease is losing ground,
but because not all cases have been identified. As a result, there is every reason to assume that the number of cases may
increase in the coming years. About this and what lessons were learned in Kyrgyzstan in 2020, when the detection of tuberculosis was difficult.
Conclusions. The new COVID-19 infection has exacerbated the problems of tuberculosis. There is a possibility of deterioration of the epidemic situation regarding the spread of tuberculosis against the background of COVID-19. This problem may have an adverse effect on the incidence of tuberculosis i

Purpose of the study. To reveal ethical grounds in the Kyrgyz culture for effective communication with local
communities in the framework of public health emergency preparedness in Kyrgyzstan.
Material and methods. Five sources with Kyrgyz proverbs and sayings were studied by the method of qualitative documentary analysis. Topics for analysis: "health"; "welfare"; "good" and related topics; topics related to social solidarity.
Results and discussion. The fifty-nine proverbs and sayings were analysed with the following results: “den-sooluk”
(health) 8.47%; "el" "kөpchuluk", "kөp", "zhurt" (people) 44.1%; "suyuu" (love), "zhakshy", "zhakshylyk" (good) 15.3%;
"birdik" (unity), "yntymak" (concord) 32.2%. The following Kyrgyz values system was revealed as ethical grounds for
social solidarity: “People” (44.1%); "Unity" and "Concord" with people (32. 2%); "Love" and "Good" (15.3%) to people;
individual "Health" (8.47 %). The existence of this system is proved by the collective customs and rituals of "Bata",
"Ashar" and "Tulөө", as well as positive biochemical, neuroendocrine, and physiological changes in the body of their
performers. Our theory: people, referring to their cultural values through the performance of collective rituals and customs,
mobilize positive neuroendocrine, biochemical, and social factors that enhance group identity, collective consciousness,
and social solidarity, thereby increasing the resilience of the people, timely and effectively adapting and recovering,
which helps reduce the negative impact of emergencies on people, the economy and public health.
Conclusions. In creating effective communication systems with Kyrgyz communities, it is important to use this revealed
values system: community is the highest good; unity and harmony, achieved through love and care of one's community
are determinants for individual health and well-being. It is important for the public health emergencies preparedness policymakers to consider the identified value system as ethical grounds for effective and just interaction with local communities.

Introduction. The World Health Organization (WHO) has been implementing a program for the elimination of measles and rubella in the world, including in the Kyrgyz Republic, for 20 years. Despite routine vaccination, measles
eradication is not smooth. Unstable vaccination, refusal of the vaccine precedes the preservation of the urgency of the
problem of measles and rubella. Over the past 10 years, 159 cases of rubella and 287 cases of measles have been registered
in the Kyrgyz Republic. At the same time, the largest number of cases of the disease this year falls on the Osh region, from January 2023 to the present, an outbreak of measles has been registered in 238 cases. The purpose of the study was to describe and assess the epidemic situation of measles in the Osh region of the Kyrgyz
Republic and to identify aggravation factors.
Materials and methods. Research methods epidemiological investigation, descriptive and evaluative epidemiological
methods. The materials for the study were statistical reporting data on the incidence of measles and rubella, laboratory
data and cases of diseases treated in the hospital by residents of the Osh region.
Results and discussion. The conducted epidemiological investigations showed that in the regions of the Osh region, a
high proportion of registered cases were the city of Osh (76 people /31.9%) and the Kara-Sui district (108/45.4%). This
is characterized by nosocomial infections, a large number of internal migration in Osh and Kara Sui district. The age distribution of morbidity cases ranged from 1 year to 34 years and a high proportion is under the age of 1 year. The analysis
of the immune status of the sick confirms that persons not vaccinated for measles were the causes of new outbreaks.
Conclusion. The increase in the incidence of measles was noted in all age categories with a high proportion between the
ages of 1 and 3 years. The factors of exacerbation of the epidemic situation of measles in the Osh region were: insufficient
compliance with anti-epidemic measures when identifying a patient at the hospital level, the first case of measles was
hospitalized in a general ward for treatment. Internal migration and refusal of vaccinations remain risks of new cases of
diseases.

Introduction. Food products are the most important factor affecting human life, which requires state regulation
of compliance with the quality and safety of food products at the legislative and economic level. In this aspect, the problem
of production and sale of high-quality food products, as well as issues of normative-legal regulation of food poisoning,
is acute for the Kyrgyz Republic today. It is clear that the fundamental task of the state is to constantly improve the regulatory
and legal mechanisms for ensuring safe nutrition of citizens of the country. Along with this, there is an urgent
need to develop state regulatory institutions in cooperation with interested communities to ensure quality control and
food safety. In the presented work, an attempt is made to analyze the legal basis for ensuring food safety in the Kyrgyz
Republic.
Objective: A preformative to improve the normative-legal regulation of food poisoning and food safety problems in the
Kyrgyz Republic.
Methods. Analysis of the normative-legal regulation of food poisoning problems in the context of food safety in the
Kyrgyz Republic and in the CIS countries (laws, Government resolutions, Codes). Results. Today, normative legal acts (laws, government resolutions, codes and orders) require immediate improvement
to solve the problems of food poisoning in the context of food safety. In the current regulatory and legal acts regarding
the problem of food safety and food poisoning have advantages and disadvantages, which requires regulation in the
context of international standards.
Conclusion. The food safety of the state is one of the most important priorities for today. From this it is necessary to
distinguish two main principles that need to befixed in legislation - the principle of ensuring the safety of food for
human health and responsibility for the production of dangerous food raw materials.

Introduction. The paper provides an overview analysis of the data of modern literature on the use of the principles
of a systematic approach as the main mechanism in the management of a healthcare organization. This approach
proceeds from the fact that the development of plans for diversified and decentralized production is subject to the interests
of the interaction of structural units that make up an integral organization. A systematic approach to the management of
an organization involves considering management as a procedure or process of making the right organizational decisions,
supported by the results of an objective comprehensive system analysis. The application of the conditions of a systematic
approach in the field of healthcare makes it possible in the future to improve the management process of medical organizations
based on the correct choice of goals and strategies aimed at improving the effective operation of multidisciplinary
hospitals, taking into account the results of a systematic analysis and choosing the most appropriate version of at least
two alternative options for effective achievement of a certain long-term goal. In the process of system analysis, goals are
identified, their priorities, interrelations and contradictions are established. Based on the goals, strategies for the development
of the organization, department, group, i.e. the subject under study, are being developed. The structure of the organization
is considered as a derivative of the goals. Healthcare management is management, whose object is a
socio-economic and complex dynamic open system. System management in the field of healthcare as a science of management,
regulation and control of labor, material and financial resources of the industry is aimed at reducing the losses
of society from mortality, morbidity and disability of the population with available resources. A systematic approach in
the management of a medical organization is recommended for possible use in the practical activities of the healthcare
system.
Objective: to conduct a review analysis of the data of modern literature on the use of the principles of a systematic approach
as the main mechanism in the management of a healthcare organization.
Methods. Analysis of the collected literature data, taking into account the possible prospective application of the principles
of a systematic approach in the management of medical organizations.
Results.A systematic approach in the management of healthcare organizations is important for making managerial decisions,
recommendations on the choice of goals and strategies (using various methods and approaches) aimed at improving
the effective performance of the organization based on system analysis and choosing the most correct version of alternative
options.
Conclusion. Based on the analysis of modern literature devoted to the use of the principles of a systematic approach, it
can be concluded that their application in the field of healthcare makes it possible to improve the management process
of medical organizations to effectively achieve a certain long-term goal. A systematic approach in the management of a
healthcare organization is recommended for possible use in practical activities.

The article presents data on the first years of the organization of the Department of Children's Diseases at the
Kyrgyz State Medical Institute and the further expansion of pediatric departments, substantiates the positive role of the
departments in the training of pediatricians and scientists, in reducing child morbidity and mortality in Kyrgyzstan.